منابع مشابه
Viroids: the minimal non-coding RNAs with autonomous replication.
Viroids are small (246-401 nucleotides), non-coding, circular RNAs able to replicate autonomously in certain plants. Viroids are classified into the families Pospiviroidae and Avsunviroidae, whose members replicate in the nucleus and chloroplast, respectively. Replication occurs by an RNA-based rolling-circle mechanism in three steps: (1). synthesis of longer-than-unit strands catalyzed by host...
متن کاملThe Role of Long Non-Coding RNAs in Ovarian Cancer
Background: Ovarian cancer is the most fatal tumor of female's reproductive system, and several genetics and environmental factors are involved in its development. Various studies have already identified suitable biomarkers to facilitate the early detection, prognosis evaluation, and the assessment of treatment response. However, the aim of this review was to investigate the role of long non-co...
متن کاملAutocatalytic sets of self-replicating RNAs
Motivation and Background The origin of life (OoL) on earth is still in search of a satisfactory explanation. The field is dominated by many facets and partial explanations. Facets include frequency of planetary systems, climatology of early earth, chirality in naturally occurring compounds, abiotic production of molecules, etc. Partial explanations include the naturally occurring self-reproduc...
متن کاملLong non-coding RNAs and their significance in human diseases
Protein-coding genes account for only a small fraction of the human genome and most of the genomic sequences are transcriptionally silent, but recent observations indicate significant functional elements, including non-coding protein transcripts in the human genome. Long non-coding RNAs (lncRNAs) have been defined as transcripts of >200 nucleotides without protein-coding capacity that perform t...
متن کاملViroids: unusual small pathogenic RNAs.
Viroids are small (about 300 nucleotides), single-stranded, circular, non-encapsidated pathogenic RNA molecules. They do not code for proteins and thus depend on plant host enzymes for their replication and other functions. They induce plant diseases by direct interaction with host factors but the mechanism of pathogenicity is still unknown. They can alter the expression of selected plant genes...
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ژورنال
عنوان ژورنال: Kagaku To Seibutsu
سال: 2004
ISSN: 0453-073X,1883-6852
DOI: 10.1271/kagakutoseibutsu1962.42.508